| A Day to Remember | Marquee Theatre | Wednesday, May 5, 2010, 6:30 pm |
| Alkaline Trio | Marquee Theatre | Tuesday, March 30, 2010, 6:30 pm |
| Angels and Airwaves | Marquee Theatre | Tuesday, May 25, 2010, 6:30 pm |
| Arctic Monkeys | Marquee Theatre | Thursday, April 15, 2010, 6:30 pm |
| Atomic Punks | Marquee Theatre | Saturday, April 17, 2010, 6:30 pm |
| Authority Zero | Marquee Theatre | Friday, April 16, 2010, 6:00 pm |
| B/S | Marquee Theatre | Saturday, March 20, 2010, 6:30 pm |
| Bullet for My Valentine | Marquee Theatre | Tuesday, May 11, 2010, 5:30 pm |
| Coheed & Cambria | Marquee Theatre | Monday, May 3, 2010, 6:00 pm |
| Fear Factory | Marquee Theatre | Monday, March 22, 2010, 6:00 pm |
| Hank III | Marquee Theatre | Tuesday, March 23, 2010, 6:30 pm |
| Infected Mushroom | Marquee Theatre | Friday, April 9, 2010, 8:00 pm |
| Kevin Nealon | Tempe Improv | September 24, 2010 - September 25, 2010 |
| Kottonmouth Kings | Marquee Theatre | Friday, April 23, 2010, 6:30 pm |
| Los Tigres del Norte | Gammage Auditorium | Friday, April 16, 2010, 8:00 pm |
| Nonpoint | Marquee Theatre | Sunday, April 4, 2010, 6:30 pm |
| Owl City | Marquee Theatre | Saturday, April 10, 2010, 5:30 pm |
| Pretty Lights | Marquee Theatre | Monday, April 19, 2010, 8:00 pm |
| Roger Clyne | Marquee Theatre | March 26, 2010 - March 27, 2010 |
| Sia | Marquee Theatre | Tuesday, April 20, 2010, 6:30 pm |
| The Ap Tour | Marquee Theatre | Wednesday, March 24, 2010, 5:30 pm |
| Vampire Weekend | Marquee Theatre | Tuesday, April 13, 2010, 7:00 pm |
| White Rabbits | The Clubhouse | Friday, April 16, 2010, 8:00 pm |
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| Alex Reymundo | Tempe Improv | June 11, 2010 - June 12, 2010 |
| Alonzo Bodden | Tempe Improv | August 12, 2010 - August 14, 2010 |
| Bobcat Goldthwait | Tempe Improv | April 2, 2010 - April 3, 2010 |
| Brian Posehn | Tempe Improv | May 7, 2010 - May 8, 2010 |
| Comedian Bob Marley | Tempe Improv | May 20, 2010 - May 22, 2010 |
| Flip Orley | Tempe Improv | April 16, 2010 - April 18, 2010 |
| Greg Fitzsimmons | Tempe Improv | April 22, 2010 - April 24, 2010 |
| In the Heights | Gammage Auditorium | June 15, 2010 - June 20, 2010 |
| Jamie Kennedy | Tempe Improv | April 30, 2010 - May 2, 2010 |
| JB Smoove | Tempe Improv | September 9, 2010 - September 11, 2010 |
| Jesus Christ Superstar | Gammage Auditorium | April 6, 2010 - April 11, 2010 |
| Jim Breuer | Tempe Improv | May 13, 2010 - May 15, 2010 |
| Josh Blue | Tempe Improv | July 29, 2010 - July 31, 2010 |
| Maz Jobrani | Tempe Improv | October 15, 2010 - October 16, 2010 |
| Michael McDonald - Comedian | Tempe Improv | June 17, 2010 - June 19, 2010 |
| Pablo Francisco | Tempe Improv | March 19, 2010 - March 21, 2010 |
| Ralphie May | Tempe Improv | August 26, 2010 - August 28, 2010 |
| Rowdy Roddy Piper | Tempe Improv | Wednesday, March 24, 2010, 8:00 pm |
| Steve Byrne | Tempe Improv | July 15, 2010 - July 17, 2010 |
| The 39 Steps | Gammage Auditorium | April 20, 2010 - April 25, 2010 |
| Tom Green | Tempe Improv | March 25, 2010 - March 27, 2010 |
| Tommy Davidson | Tempe Improv | June 3, 2010 - June 5, 2010 |
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