| Baltimore Orioles | Camden Yards | April 9, 2010 - October 3, 2010 |
| Baltimore Ravens | M&T Bank Stadium | Saturday, September 11, 2010, TBA |
| Black Eyed Susan Stakes | Pimlico Race Course | Friday, May 14, 2010, TBA |
| Maryland Terrapins Football | M&T Bank Stadium | Monday, September 6, 2010, 4:00 pm |
| Navy Midshipmen Football | M&T Bank Stadium | Saturday, September 4, 2010, TBA |
| NCAA Lacrosse Championships | M&T Bank Stadium | May 29, 2010 - May 31, 2010 |
| Preakness Stakes | Pimlico Race Course | Saturday, May 15, 2010, TBA |
| Shogun Fights | 1st Mariner Arena | Saturday, March 27, 2010, 6:00 pm |
| WWE - World Wrestling Entertainment | 1st Mariner Arena | Sunday, April 25, 2010, 7:45 pm |
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| 2u: a Tribute To U2 | Rams Head Live | Saturday, April 17, 2010, 9:00 pm |
| Alicia Keys | 1st Mariner Arena | Wednesday, March 24, 2010, 7:30 pm |
| Arctic Monkeys | Rams Head Live | Wednesday, April 7, 2010, 8:00 pm |
| BB King | Pier Six Concert Pavilion | Thursday, July 15, 2010, 6:00 pm |
| Beach Boys | Pier Six Concert Pavilion | Saturday, July 24, 2010, 8:00 pm |
| Ben Harper | Pier Six Concert Pavilion | April 20, 2010 - May 5, 2010 |
| Bone Thugs N Harmony | Rams Head Live | Thursday, April 8, 2010, 8:00 pm |
| Bullet for My Valentine | Rams Head Live | Sunday, May 2, 2010, 8:00 pm |
| Charlie Wilson | Pier Six Concert Pavilion | Friday, June 25, 2010, 7:30 pm |
| Citizen Cope | Rams Head Live | Saturday, April 24, 2010, TBA |
| Daughtry | 1st Mariner Arena | Thursday, March 18, 2010, 7:30 pm |
| Dave Koz | Pier Six Concert Pavilion | Friday, July 30, 2010, 7:30 pm |
| David Gray | Lyric Opera House | Wednesday, March 31, 2010, 8:00 pm |
| Drake | Pier Six Concert Pavilion | Wednesday, May 5, 2010, 7:00 pm |
| Earth Wind & Fire | Pier Six Concert Pavilion | Friday, June 18, 2010, 6:00 pm |
| Frontiers | Rams Head Live | Friday, April 16, 2010, 8:00 pm |
| Get the Led Out | Rams Head Live | Saturday, May 15, 2010, 8:00 pm |
| Hall & Oates | Pier Six Concert Pavilion | Sunday, June 6, 2010, 6:00 pm |
| Jakob Dylan | Rams Head Live | Thursday, April 22, 2010, 7:00 pm |
| Josh Gracin | Rams Head Live | Friday, April 23, 2010, 7:00 pm |
| Julian Casablancas | Rams Head Live | Sunday, March 28, 2010, 7:00 pm |
| Kenny Loggins | Pier Six Concert Pavilion | Saturday, May 15, 2010, 8:00 pm |
| Mastodon | Rams Head Live | Tuesday, April 20, 2010, 6:00 pm |
| Michael Franti & Spearhead | Pier Six Concert Pavilion | Saturday, May 29, 2010, 5:00 pm |
| Mr. Greengenes | Rams Head Live | Friday, March 26, 2010, 10:00 pm |
| Norah Jones | Lyric Opera House | Tuesday, March 30, 2010, 8:00 pm |
| OK Go | Rams Head Live | Sunday, May 9, 2010, 9:00 pm |
| REO Speedwagon | Pier Six Concert Pavilion | Saturday, September 4, 2010, 5:30 pm |
| Steel Panther | Rams Head Live | Friday, April 9, 2010, 8:00 pm |
| The Big Pink | Rams Head Live | Thursday, April 1, 2010, 9:00 pm |
| The xx | Sonar | Friday, April 23, 2010, 9:00 pm |
| Wale | Rams Head Live | Saturday, April 3, 2010, 9:00 pm |
| Willie Nelson | Pier Six Concert Pavilion | Sunday, July 25, 2010, 7:30 pm |
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| Carol Burnett | Lyric Opera House | Saturday, April 3, 2010, 7:30 pm |
| David Sedaris | Meyerhoff Symphony Hall | Saturday, April 10, 2010, 8:00 pm |
| Jeff Foxworthy | 1st Mariner Arena | Saturday, May 1, 2010, 8:00 pm |
| Laurie Berkner | Pier Six Concert Pavilion | Saturday, May 1, 2010, 2:00 pm |
| Lisa Lampanelli | Meyerhoff Symphony Hall | Friday, April 16, 2010, 8:00 pm |
| Mike Epps | 1st Mariner Arena | Saturday, March 20, 2010, 8:00 pm |
| Phantom Of The Opera | Hippodrome Performing Arts Center | April 4, 2010 - May 9, 2010 |
| Stomp | Hippodrome Performing Arts Center | March 16, 2010 - March 28, 2010 |
| The 39 Steps | Hippodrome Performing Arts Center | June 1, 2010 - June 13, 2010 |
| Tracy Morgan | Lyric Opera House | Thursday, April 29, 2010, 8:00 pm |
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