| A. R. Rahman | Toyota Center - TX | Saturday, July 3, 2010, 8:30 pm |
| Al Green | Houston Arena Theatre | Sunday, May 16, 2010, 8:00 pm |
| Alejandro Fernandez | Toyota Center - TX | Friday, May 28, 2010, 8:00 pm |
| Alicia Keys | Toyota Center - TX | Saturday, April 3, 2010, 8:00 pm |
| Angels and Airwaves | House of Blues - Houston | Tuesday, May 18, 2010, 7:00 pm |
| Angie Stone | Houston Arena Theatre | Friday, March 26, 2010, 8:00 pm |
| Ani DiFranco | Warehouse Live | Thursday, April 8, 2010, 7:00 pm |
| Aqua Teen Hunger Force | House of Blues - Houston | Friday, April 16, 2010, 8:00 pm |
| Bamboozle | Verizon Wireless Theater-TX | Friday, May 28, 2010, TBA |
| Black Rebel Motorcycle Club | House of Blues - Houston | Saturday, March 20, 2010, 7:00 pm |
| Blue October | Sam Houston Race Park | Saturday, May 15, 2010, 8:45 pm |
| Bone Thugs N Harmony | House of Blues - Houston | Thursday, April 22, 2010, 10:00 pm |
| Celtic Woman | Toyota Center - TX | Friday, April 30, 2010, 8:00 pm |
| Clint Black | Houston Arena Theatre | Friday, October 1, 2010, 9:00 pm |
| Cobra Starship | Verizon Wireless Theater-TX | Saturday, June 5, 2010, 6:00 pm |
| Coheed & Cambria | Warehouse Live | Tuesday, April 27, 2010, 8:00 pm |
| Edwin McCain | House of Blues - Houston | Friday, April 2, 2010, 8:30 pm |
| El Chapo De Sinaloa | House of Blues - Houston | Friday, March 26, 2010, 8:00 pm |
| Emily Osment | House of Blues - Houston | Saturday, April 10, 2010, 5:00 pm |
| Enrique Bunbury | House of Blues - Houston | Tuesday, April 27, 2010, 7:00 pm |
| Frankie Valli & The Four Seasons | Jones Hall | Friday, April 23, 2010, 7:30 pm |
| Gipsy Kings | House of Blues - Houston | Friday, May 7, 2010, 7:30 pm |
| Green River Ordinance | House of Blues - Houston | Friday, April 23, 2010, 7:00 pm |
| HIM | House of Blues - Houston | Friday, April 30, 2010, 7:00 pm |
| Honor Society | House of Blues - Houston | Thursday, March 25, 2010, 7:00 pm |
| Houston Symphony | Jones Hall | April 8, 2010 - May 23, 2010 |
| Jeff Beck | Verizon Wireless Theater-TX | Saturday, April 24, 2010, 8:00 pm |
| Johnny Winter | Meridian | Friday, June 18, 2010, 7:00 pm |
| Jordin Sparks | House of Blues - Houston | Monday, May 17, 2010, 7:00 pm |
| Julian Casablancas | House of Blues - Houston | Monday, April 12, 2010, 7:00 pm |
| Keith Emerson | Verizon Wireless Theater-TX | Sunday, May 2, 2010, 8:00 pm |
| Kenny G | Houston Arena Theatre | Thursday, April 22, 2010, 8:00 pm |
| Kidz in the Hall | House of Blues - Houston | Tuesday, April 6, 2010, 7:00 pm |
| Lupe Fiasco | House of Blues - Houston | Monday, April 26, 2010, 8:00 pm |
| Marvin Hamlisch | Jones Hall | Saturday, March 27, 2010, 8:00 pm |
| Megadeth | Verizon Wireless Theater-TX | Thursday, March 25, 2010, 7:00 pm |
| Michael Buble | Toyota Center - TX | Friday, July 16, 2010, 8:00 pm |
| Norah Jones | Verizon Wireless Theater-TX | Wednesday, May 5, 2010, 8:00 pm |
| Owl City | Verizon Wireless Theater-TX | Friday, April 16, 2010, 7:00 pm |
| Phoenix | Verizon Wireless Theater-TX | Friday, April 30, 2010, 8:00 pm |
| Puddle of Mudd | House of Blues - Houston | Sunday, April 18, 2010, 7:00 pm |
| Robert Cray Band | House of Blues - Houston | Saturday, May 29, 2010, 7:30 pm |
| Sounds of Seattle | House of Blues - Houston | Friday, June 18, 2010, 8:00 pm |
| Straight No Chaser | Verizon Wireless Theater-TX | Friday, May 7, 2010, 8:00 pm |
| Taylor Swift | Toyota Center - TX | May 25, 2010 - May 26, 2010 |
| The Dead Weather | House of Blues - Houston | Saturday, May 1, 2010, 9:00 pm |
| Trans-Siberian Orchestra | Verizon Wireless Theater-TX | Saturday, May 1, 2010, 8:00 pm |
| Vans Warped Tour | Sam Houston Race Park | Friday, July 2, 2010, TBA |
| Yeasayer | House of Blues - Houston | Friday, April 9, 2010, 8:00 pm |
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| Chelsea Handler | Verizon Wireless Theater-TX | April 23, 2010 - April 23, 2010 |
| Choo Choo Soul | Verizon Wireless Theater-TX | Sunday, April 25, 2010, 1:00 pm |
| Cirque du Soleil: Alegria | Toyota Center - TX | November 10, 2010 - November 14, 2010 |
| David Sedaris | Jones Hall | Wednesday, April 28, 2010, 8:00 pm |
| Disney on Ice: Let's Celebrate | Reliant Stadium | April 14, 2010 - April 18, 2010 |
| In the Heights | Sarofim Hall- Hobby Center | April 6, 2010 - April 18, 2010 |
| Je'Caryous Johnson's Cheaper to Keep Her | Sarofim Hall- Hobby Center | Saturday, March 27, 2010, 5:00 pm |
| Lang Lang | Jones Hall | Wednesday, April 14, 2010, 8:00 pm |
| Little House on the Prairie | Sarofim Hall- Hobby Center | April 28, 2010 - May 9, 2010 |
| Mike Epps | Reliant Arena | Saturday, March 27, 2010, 8:00 pm |
| Monique | Reliant Arena | Saturday, April 17, 2010, 8:00 pm |
| Porcupine Tree | House of Blues - Houston | Wednesday, April 21, 2010, 8:00 pm |
| Thunder from Down Under | House of Blues - Houston | Tuesday, April 13, 2010, 8:00 pm |
| Wicked | Sarofim Hall- Hobby Center | June 30, 2010 - July 25, 2010 |
| Young Frankenstein | Sarofim Hall- Hobby Center | May 25, 2010 - June 6, 2010 |
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